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pam50 bioclassifier panel  (Bioclassifier LLC)

 
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    Structured Review

    Bioclassifier LLC pam50 bioclassifier panel
    Cohort characteristics
    Pam50 Bioclassifier Panel, supplied by Bioclassifier LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/pam50+bioclassifier+panel/breast+pam50+subtyping+assay/pmc03743663-97-21-22
    Average 90 stars, based on 1 article reviews
    pam50 bioclassifier panel - by Bioz Stars, 2026-09
    90/100 stars

    Images

    1) Product Images from "A 50-Gene Intrinsic Subtype Classifier for Prognosis and Prediction of Benefit from Adjuvant Tamoxifen"

    Article Title: A 50-Gene Intrinsic Subtype Classifier for Prognosis and Prediction of Benefit from Adjuvant Tamoxifen

    Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

    doi: 10.1158/1078-0432.CCR-12-0286

    Cohort characteristics
    Figure Legend Snippet: Cohort characteristics

    Techniques Used:

    Intrinsic subtype distribution by immunohistochemistry and PAM50 ( n = 348)
    Figure Legend Snippet: Intrinsic subtype distribution by immunohistochemistry and PAM50 ( n = 348)

    Techniques Used: Immunohistochemistry

    Prognosis based on PAM50 classifier for DFS (A) and OS (B).
    Figure Legend Snippet: Prognosis based on PAM50 classifier for DFS (A) and OS (B).

    Techniques Used:

    A, Kaplan–Meier curves for DFS among ER+ (local assessment) patients for tamoxifen versus placebo. B, Kaplan–Meier curves for DFS among luminal subtypes by immunohistochemistry for tamoxifen versus placebo. C, Kaplan–Meier curves for DFS among luminal subtypes by PAM50 for tamoxifen versus placebo.
    Figure Legend Snippet: A, Kaplan–Meier curves for DFS among ER+ (local assessment) patients for tamoxifen versus placebo. B, Kaplan–Meier curves for DFS among luminal subtypes by immunohistochemistry for tamoxifen versus placebo. C, Kaplan–Meier curves for DFS among luminal subtypes by PAM50 for tamoxifen versus placebo.

    Techniques Used: Immunohistochemistry

    Related Articles

    Polymerase Chain Reaction:

    Article Title: A 50-Gene Intrinsic Subtype Classifier for Prognosis and Prediction of Benefit from Adjuvant Tamoxifen
    Article Snippet: .. PCR primers optimized for use on FFPEmaterials were used to make quantitative measurements for a panel of 50 discriminatory genes (PAM50 bioclassifier panel) to segregate tumors into luminal A, luminal B, HER-2–enriched, basal-like, and normal breast–like expression profiles (19). ..

    Article Title: A 50-Gene Intrinsic Subtype Classifier for Prognosis and Prediction of Benefit from Adjuvant Tamoxifen
    Article Snippet: .. PCR primers optimized for use on FFPE materials were used to make quantitative measurements for a panel of 50 discriminatory genes (PAM50 bioclassifier panel) to segregate tumors into luminal A, luminal B, HER-2-enriched, basal-like, and normal breast–like expression profiles ( 19 ). ..

    Expressing:

    Article Title: A 50-Gene Intrinsic Subtype Classifier for Prognosis and Prediction of Benefit from Adjuvant Tamoxifen
    Article Snippet: .. PCR primers optimized for use on FFPEmaterials were used to make quantitative measurements for a panel of 50 discriminatory genes (PAM50 bioclassifier panel) to segregate tumors into luminal A, luminal B, HER-2–enriched, basal-like, and normal breast–like expression profiles (19). ..

    Article Title: A 50-Gene Intrinsic Subtype Classifier for Prognosis and Prediction of Benefit from Adjuvant Tamoxifen
    Article Snippet: .. PCR primers optimized for use on FFPE materials were used to make quantitative measurements for a panel of 50 discriminatory genes (PAM50 bioclassifier panel) to segregate tumors into luminal A, luminal B, HER-2-enriched, basal-like, and normal breast–like expression profiles ( 19 ). ..

    Quantitative RT-PCR:

    Article Title: A 50-Gene Intrinsic Subtype Classifier for Prognosis and Prediction of Benefit from Adjuvant Tamoxifen
    Article Snippet: .. We investigated the prognostic and predictive value of classifying breast cancers into intrinsic subtypes by qRT-PCR with the PAM50 bioclassifier panel using material from a randomized controlled trial comparing tamoxifen with placebo in premenopausal women also treated with adjuvant chemotherapy (MA.12). ..

    Adjuvant:

    Article Title: A 50-Gene Intrinsic Subtype Classifier for Prognosis and Prediction of Benefit from Adjuvant Tamoxifen
    Article Snippet: .. We investigated the prognostic and predictive value of classifying breast cancers into intrinsic subtypes by qRT-PCR with the PAM50 bioclassifier panel using material from a randomized controlled trial comparing tamoxifen with placebo in premenopausal women also treated with adjuvant chemotherapy (MA.12). ..

    Formalin-fixed Paraffin-Embedded:

    Article Title: A 50-Gene Intrinsic Subtype Classifier for Prognosis and Prediction of Benefit from Adjuvant Tamoxifen
    Article Snippet: .. PCR primers optimized for use on FFPE materials were used to make quantitative measurements for a panel of 50 discriminatory genes (PAM50 bioclassifier panel) to segregate tumors into luminal A, luminal B, HER-2-enriched, basal-like, and normal breast–like expression profiles ( 19 ). ..



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    Pam50 Bioclassifier Panel, supplied by Bioclassifier LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Image Search Results


    Cohort characteristics

    Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

    Article Title: A 50-Gene Intrinsic Subtype Classifier for Prognosis and Prediction of Benefit from Adjuvant Tamoxifen

    doi: 10.1158/1078-0432.CCR-12-0286

    Figure Lengend Snippet: Cohort characteristics

    Article Snippet: PCR primers optimized for use on FFPE materials were used to make quantitative measurements for a panel of 50 discriminatory genes (PAM50 bioclassifier panel) to segregate tumors into luminal A, luminal B, HER-2-enriched, basal-like, and normal breast–like expression profiles ( 19 ).

    Techniques:

    Intrinsic subtype distribution by immunohistochemistry and PAM50 ( n = 348)

    Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

    Article Title: A 50-Gene Intrinsic Subtype Classifier for Prognosis and Prediction of Benefit from Adjuvant Tamoxifen

    doi: 10.1158/1078-0432.CCR-12-0286

    Figure Lengend Snippet: Intrinsic subtype distribution by immunohistochemistry and PAM50 ( n = 348)

    Article Snippet: PCR primers optimized for use on FFPE materials were used to make quantitative measurements for a panel of 50 discriminatory genes (PAM50 bioclassifier panel) to segregate tumors into luminal A, luminal B, HER-2-enriched, basal-like, and normal breast–like expression profiles ( 19 ).

    Techniques: Immunohistochemistry

    Prognosis based on PAM50 classifier for DFS (A) and OS (B).

    Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

    Article Title: A 50-Gene Intrinsic Subtype Classifier for Prognosis and Prediction of Benefit from Adjuvant Tamoxifen

    doi: 10.1158/1078-0432.CCR-12-0286

    Figure Lengend Snippet: Prognosis based on PAM50 classifier for DFS (A) and OS (B).

    Article Snippet: PCR primers optimized for use on FFPE materials were used to make quantitative measurements for a panel of 50 discriminatory genes (PAM50 bioclassifier panel) to segregate tumors into luminal A, luminal B, HER-2-enriched, basal-like, and normal breast–like expression profiles ( 19 ).

    Techniques:

    A, Kaplan–Meier curves for DFS among ER+ (local assessment) patients for tamoxifen versus placebo. B, Kaplan–Meier curves for DFS among luminal subtypes by immunohistochemistry for tamoxifen versus placebo. C, Kaplan–Meier curves for DFS among luminal subtypes by PAM50 for tamoxifen versus placebo.

    Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

    Article Title: A 50-Gene Intrinsic Subtype Classifier for Prognosis and Prediction of Benefit from Adjuvant Tamoxifen

    doi: 10.1158/1078-0432.CCR-12-0286

    Figure Lengend Snippet: A, Kaplan–Meier curves for DFS among ER+ (local assessment) patients for tamoxifen versus placebo. B, Kaplan–Meier curves for DFS among luminal subtypes by immunohistochemistry for tamoxifen versus placebo. C, Kaplan–Meier curves for DFS among luminal subtypes by PAM50 for tamoxifen versus placebo.

    Article Snippet: PCR primers optimized for use on FFPE materials were used to make quantitative measurements for a panel of 50 discriminatory genes (PAM50 bioclassifier panel) to segregate tumors into luminal A, luminal B, HER-2-enriched, basal-like, and normal breast–like expression profiles ( 19 ).

    Techniques: Immunohistochemistry